The coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is a highly virulent virus. Evidence suggests that disruption of host ...

Shifting brain glucose levels act as a metabolic switch that directs OPC proliferation and myelin formation, revealing a mechanism with developmental and clinical implications.

Strands of DNA wrapped around a histone. Credit: Molekuul/Science Source Histones are among the most abundant proteins in the body. They act as spools that help compact DNA so our enormous genomes ...

Nearly two years into the pandemic, we find ourselves thinking about viruses daily. Amid the dread of hearing about yet another new SARS-CoV-2 variant and longing for normalcy, perhaps you’ve ...

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

DNA does not float freely in the cell. Instead, it is wrapped around histone proteins to form structures called nucleosomes.

Our group has contributed to the molecular and functional understanding of histone mark and DNA methylation mark readout by writer, reader and eraser proteins, as well as investigated the crosstalk ...

There is perhaps no more fundamental property of life than change, both with respect to personal experience and, as the basis of evolution, to the nature of biology itself. The constant genetic ...

The olfactory system is essential for most animals: it supports postnatal survival, detects environmental hazards and mediates emotional, social and nutritional behaviors.

What is the histone code? Different chemical marks, such as acetylation, methylation, or phosphorylation, are made to numerous residues on the N-terminal tails of histone proteins. Some posit that ...