Silencing mRNA expression in dendritic cells did not impair T‑cell priming, including for SARS‑CoV‑2 antigens, suggesting that cross‑presentation by other cell types is sufficient to initiate immunity ...

Differentiated hepatocyte organoids formed networks of small canals that allowed bile acid to pass, in a manner similar to human tissue. While organoids aim to mimic human organs, the liver’s ...

In mammals, the liver detects the body's energy demand at any given moment and mobilizes nutrient reserves to meet it. It is a vital function that is subdivided into multiple tasks: from releasing ...

In early-stage drug discovery, in vitro models are essential for generating clinically relevant data that expedite the progress of potential therapeutics into clinical trials. However, most ...

Researchers used a microfluidic device to generate hydrogel microspheres of uniform shape and size. These spheres are then mixed with hepatocytes and injected into the body, where they form stable ...